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Scorpion venom to prevent heart failure

Scorpions are one of the harmful insects. Because, almost all species of scorpions have venom. In general, scorpion venom is included as neurotoxins (nerve poisons). But there is one type of scorpion toxins that have included in the category of cytotoxic (cell toxic), which Hemiscorpius lepturus.

Neurotoxins comprise small proteins as well as sodium and potassium, which are useful to interfere with nerve transmission. Scorpion venom used to capture prey, the self-defense and for the marriage. All scorpions have venom and can sting. Scorpion venom is a complex mixture of neurotoxins or nerve toxins and other materials. Each type has a unique blend.

There are several types of scorpion venom can be deadly dangerous because, among other things:

  • Centruroides exilicauda (widely available in the United States)
  • Androctonus, Buthus, Hottentotta, Leiurus (North Africa and Middle East)
  • Bark Scorpion (Central America)
  • Tityus (South America)
  • Mesobuthus (India)
  • Centruroides (Mexico)
  • And there are some more types that spread throughout the world.

Some studies assumed mortality cases in the hospital about 4% in children who are more susceptible than older ones. In the event of death through is generally caused by cardiac and respiratory failure several hours after death. Scorpions are most likely to cause human deaths is Androctonus australis.

Some types of scorpions have venom in the category is very dangerous, but if processed correctly, venom has the potential to cure diseases, one of which prevent heart failure.

If someone is experiencing cardiac disorders, the treatment required is bypass surgery. This operation is performed to improve blood flow to the heart in people who are known to have severe coronary disease so the risk of heart attack. During surgery, a healthy artery or vein from another part of the body is connected to the blocked coronary artery. The new route will bring oxygen-rich blood to the heart muscle. However, this operation can fail if it clogged vein grafts.

Scientists from the University of Leeds have discovered that the toxin margatoxin contained in the bark scorpion, which are found Central America could be a solution. The results of a study published in Cardiovascular Research discovered the toxin has the power of at least 100 times more potent than other compounds to prevent vein graft failure.

"This poison works by suppressing the natural response of blood vessels to injury so keeping the blood vessels clean. Effectiveness toxin makes us surprised and only takes a few molecules to get the effect," says Professor Beech (chief researcher) as quoted from Dailymail.

Professor Beech said margatoxin this possibility can be given in the form of a drug that is swallowed, inhaled or injected. But it could also potentially as a spray medicine into the veins themselves while waiting for a heart transplant operation.

Heart disease is still to be one of the feared heart disease and bypass surgery a success that can last about 10-15 years. It is hoped the discovery margatoxin of the bark scorpion can reduce the failure rate in patients with cardiac bypass surgery, which can increase life expectancy.
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